Tight junctions in the blood–brain barrier promote edema formation and infarct size in stroke – Ambivalent effects of sealing proteins:

Lars Winkler,Rosel Blasig,Olga Breitkreuz-Korff,Philipp Berndt,Sophie Dithmer,Hans Christian Cederberg Helms,Dmytro Puchkov,Kavi Devraj,Mehmet Kaya,Zhihai Qin,Stefan Liebner,Hartwig Wolburg,Anuska V. Andjelkovic,Andre Rex,Ingolf E. Blasig,Reiner F. Haseloff

Tight junctions in the blood–brain barrier promote edema formation and infarct size in stroke – Ambivalent effects of sealing proteins:

2020

Lars Winkler
Rosel Blasig
Olga Breitkreuz-Korff
Philipp Berndt
Sophie Dithmer
Hans Christian Cederberg Helms
Dmytro Puchkov
Kavi Devraj
Mehmet Kaya
Zhihai Qin
Stefan Liebner
Hartwig Wolburg
Anuska V. Andjelkovic
Andre Rex
Ingolf E. Blasig
Reiner F. Haseloff

The outcome of stroke is greatly influenced by the state of the blood–brain barrier (BBB). The BBB endothelium is sealed paracellularly by tight junction (TJ) proteins, i.e., claudins (Cldns) and t...

Keywords:

Diabetes mellitus
Tight junction
Edema
Anesthesia
Stroke
Endothelium
Claudin
Biology
Occludin
Blood–brain barrier
Pathology
edema formation

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