Correlation of botulinum toxin dosage and GMFCS level in children with bilateral spastic cerebral palsy – An explorative cohortstudy

Introduction: Multi-level treatment with botulinum toxin type A (BoNT/A; Botox®) plays a central role within the integrative treatment strategy in children with cerebral palsy (CP). Goal of this study was to analyse the dosage/kg bodyweight (b.w.) in correlation to the severity of CP according to GMFCS level and to prove the hypothesis, that dosage is not severity dependent but correlates to the number of treated muscles.