Effect of Exogenous Melatonin on Rat Haematopoietic Cells Exposed to Cytosine Arabinoside and Etoposide Wpływ egzogennej melatoniny na układ krwiotwórczy szczurów poddanych działaniu arabinozydu cytozyny i etopozydu

Background. There are reports that melatonin may protect the bone marrow cells from apoptosis induced by the chemotherapy especially by anthracyclines. Objectives. The aim of the study was to determine whether exogenous melatonin can protect the bone marrow of rats treated with the antitumour drugs cytosine arabinoside (Ara−C) and etoposide (VP−16) widely used in haematology.