Abstract TP444: CNS Vasculitis: A Tertiary Care Center’s Experience

OBJECTIVE: CNS Vasculitis (CNSV) is a rare and ill-defined cause of stroke with limited available case series in the modern era of stroke management. The objective of this study was to evaluate CNS Vasculitis in a tertiary care cerebrovascular center DESIGN/METHODS/RESULTS: Between March 2009 and July 2012, 14 cases were coded as having cerebral vasculitis and fulfilled our criteria for CNSV which included acute onset of neurologic abnormalities in setting of angiographic guided multiple segmental narrowing in two or more CNS vessels. Patients included 5 males and 9 females between 11 and 88 years of which 3 were African-American and 11 were Caucasian. Presentations ranged from seizures in 28.6%(4/14) and stroke in 71.4% (10/14) with 40% (4/10) being hemorrhagic and 60% (6/10) ischemic, with a 33%(2/6)hemorrhagic conversion rate. 78.6% (11/14) were found to have Primary CNSV and 14.3% (2/14) had systemic vasculitis. Diagnostic modalities included cerebralangiography in 64.2% (9/14), MRA in 85% (12/14), co...