Dynamics of the human and viral m(6)A RNA methylomes during HIV-1 infection of T cells.

Gianluigi Lichinchi,Shang Gao,Yogesh Saletore,Gwendolyn González,Vikas Bansal,Yinsheng Wang,Christopher E. Mason,Tariq M. Rana

Dynamics of the human and viral m(6)A RNA methylomes during HIV-1 infection of T cells.

2016

Gianluigi Lichinchi
Shang Gao
Yogesh Saletore
Gwendolyn González
Vikas Bansal
Yinsheng Wang
Christopher E. Mason
Tariq M. Rana

Infection with HIV-1 triggers an increase in N6-methyladenosine (m6A) modification of both viral and host mRNAs, which impacts viral replication and nuclear export of viral RNA.

Keywords:

Epitranscriptomics
Viral replication
RNA
Virology
Molecular biology
Biology
Stem-loop
Regulatory sequence
RNA splicing
Gene
Messenger RNA
Genetics
Gene silencing

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