Human Amnion Epithelial Cells Produce Soluble Factors that Enhance Liver Repair by Reducing Fibrosis While Maintaining Regeneration in a Model of Chronic Liver Injury.

Alexander Hodge,Neil Andrewartha,Dinushka Lourensz,Robyn P. Strauss,Jeanne Correia,Mihiri Goonetilleke,George C.T. Yeoh,Rebecca Lim,William Sievert

Human Amnion Epithelial Cells Produce Soluble Factors that Enhance Liver Repair by Reducing Fibrosis While Maintaining Regeneration in a Model of Chronic Liver Injury.

2020

Alexander Hodge
Neil Andrewartha
Dinushka Lourensz
Robyn P. Strauss
Jeanne Correia
Mihiri Goonetilleke
George C.T. Yeoh
Rebecca Lim
William Sievert

Human amnion epithelial cells (hAECs) exert potent antifibrotic and anti-inflammatory effects when transplanted into preclinical models of tissue fibrosis. These effects are mediated in part via th...

Keywords:

Amnion
Medicine
Liver repair
Cancer research
Fibrosis
tissue fibrosis
liver fibrosis
chronic liver injury
Cell therapy

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