Effects of Exercise Training Amount and Intensity on Peak Oxygen Consumption in Middle-Age Men and Women at Risk for Cardiovascular Disease*

Study objectives Although increasing aerobic fitness by exercise training is advocated as part of a healthy lifestyle, studies examining the different effects of intensity and amount on peak consumption ( V ˙ o 2 ) remain sparse. Design This randomized controlled trial compared the effects of three different exercise regimens differing in amount and intensity on fitness improvements. Participants Overweight men and women with mild-to-moderate dyslipidemia were recruited. Interventions The exercise groups were as follows: (1) low amount/moderate intensity (LAMI, n=25), the caloric equivalent of walking 19 kilometers (km)/wk at 40 to 55% of peak V ˙ o 2 ; (2) low amount/high intensity (LAHI, n=36), the equivalent of jogging 19 km/wk at 65 to 80% of peak V ˙ o 2 ; (3) high amount/high intensity (HAHI, n=35), the equivalent of jogging 32 km/wk at 65 to 80% of peak V ˙ o 2 ; and (4) a control group (n = 37). Measurements and results Peak V ˙ o 2 and time to exhaustion (TTE) were tested before and after 7 to 9 months of training. All exercise groups increased peak V ˙ o 2 and TTE compared to baseline (p ≤ 0.001). Improvements in peak V ˙ o 2 were greater in the LAHI and HAHI groups compared to the control group (p Conclusions Exercising at a level of 19 km/wk at 40 to 55% of peak V ˙ o 2 is sufficient to increase aerobic fitness levels, and increasing either exercise intensity or the amount beyond these parameters will yield additional separate and combined effects on markers of aerobic fitness. Therefore, it is appropriate to recommend mild exercise to improve fitness and reduce cardiovascular risk yet encourage higher intensities and amounts for additional benefit.