Aggressive Costoclavicular Junction Decompression in Patients with Threatened AV Access.

Background A substantial number of patients with threatened arteriovenous (AV) access are found to have stenoses at the costoclavicular junction (CCJ), which frequently are resistant to angioplasty and stenting. We believe that stenoses in this location will not resolve unless bony decompression is performed to relieve the extrinsic compression on the vein. This article describes our short- to medium-term results following such decompression in patients with failing fistulae. Methods We reviewed a prospectively maintained database to identify all patients with threatened AV access operated on for stenoses at the CCJ. Pre- and postoperative course along with long-term follow-up were analyzed. Results Between July 2012 and December 2013, 24 patients with threatened access were operated on for CCJ stenoses at our institution. Fifteen had highly dysfunctional AV fistulae otherwise felt to need ligation, 10 had significant arm and/or head swelling, and 3 required access but had no contralateral options. In 6 patients, the subclavian vein was occluded and 18 stenotic; 5 of these had stents in place through the CCJ. Decompression was performed via claviculectomy in 3 patients, 2 of whom underwent reconstruction (one jugular vein, one prosthetic bypass) and 1 was stented. The other 21 patients underwent first rib resection, 20 via an infraclavicular exposure and 1 via a supraclavicular rib resection. A variety of interventions were performed in the arm, including aneurysm plication, cephalic to deep bypass, one prophylactic distal revascularization interval ligation, and several primary fistulae. 30-Day mortality was minimal: there was one significant hematoma and one hemothorax in a patient who underwent on-table thrombolysis and there were no deaths or cardiac, neurologic, or other significant morbidity. Median length of stay was 2 days. At follow-up up to 20 (median 10) months, 4 patients died of unrelated causes and 1 patient undergoing central reconstruction with prosthetic bypass required excision of this for infection and ligation of his fistula. Two other fistulae failed. One-year assisted primary patency of the fistula was 85%, and of the central bypass, 89%. At last follow-up, the index arm continued to be used for access in 85% of patients, and overall survival was 68%. Virtually all patients experienced dramatic symptom relief. Conclusions In this group of high-risk patients whose access was judged otherwise nonsalvageable, excellent symptom relief and long-term fistula and ipsilateral arm use can be achieved with aggressive decompression of the bony CCJ followed by endovascular intervention as needed.