Severe Pediatric Adenovirus 7 Disease in Singapore Linked to Recent Outbreaks across Asia

Oon Tek Ng,Koh Cheng Thoon,Hui Ying Chua,Natalie Woon Hui Tan,Chia Yin Chong,Nancy Wen Sim Tee,Raymond T.P. Lin,Lin Cui,Indumathi Venkatachalam,Paul A. Tambyah,Jonathan Chew,Raymond Fong,Helen M. L. Oh,Prabha Krishnan,Vernon J. Lee,Boon Huan Tan,Sock Hoon Ng,Pei-Jun Ting,Sebastian Maurer-Stroh,Vithiagaran Gunalan,Wei Xin Khong

Severe Pediatric Adenovirus 7 Disease in Singapore Linked to Recent Outbreaks across Asia

2015

During November 2012–July 2013, a marked increase of adenovirus type 7 (Ad7) infections associated with severe disease was documented among pediatric patients in Singapore. Phylogenetic analysis revealed close genetic links with severe Ad7 outbreaks in China, Taiwan, and other parts of Asia.

Keywords:

Phylogenetics
Virology
Disease
Medicine
Retrospective cohort study
Outbreak
severe disease
invasive disease
infant newborn

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