Phytochemical and some pharmacological activity of acetone extracts of some Sudanese plants

The Trigonella foenum graecum (TFG) and Artemisia annua (Aa) having medicinal value in Sudan for its use in gastrointestinal and inflammatory disorders. This study rationalizes the medicinal use of Trigonella foenum graecum and Artemisia annua separately and traditionally prepared combination of them as antispasmodic, antimicrobial, antioxidant. The antispasmodic effect was evaluated using rabbit jejunum preparation while the antioxidant activity was evaluated using DPPH method and the antimicrobial activity was studied against standard strains using paper disc diffusion method. The result was exhibited that Ethyl acetate, Acetone, Aquatic ethanol extracts of processed combined drug were induced appreciable relaxant effect on rabbit jejunum, Acetone extract of processed combined drug showed high activity against Pseudomonas aeruginosa at concentration 100 mg/ml with MIZD (31 mm). High antioxidant activity was seen with Acetone extracts of A.annua and T.foenum graecum.