The Evaluation of MRI with Total Imaging Matrix for Patients of Bone Metastases

2007 
Objective To discuss the diagnostic value of MRI with total imaging matrix(TIM)for bone metastases.Materials and Methods 25 patients with malignant tumors underwent whole body SPECT as well as MRI with total imaging matrix techniques,the results were compared.Results In 25 patients,54 malignant and 9 benign bone lesions were detected by MR TIM and SPECT.The sensitivity of TIM techniques was 93%(50/54),SPECT achieved 87%(47/54;P0.05),specificity was 67%(6/9) for TIM techniques and 56%(5/9) for SPECT(P0.05).negative predictive and positive predictive value were 60%(6/10)and 94%(50/53)for TIM techniques,and 42%(5/12)and 92%(47/51)for SPECT.Diagnostic accuracy was 89%(56/63) for MRI and 83% for SPECT(52/63;P0.001),respectively.Conclusion MRI wih TIM techniques and SPECT are useful imaging modalities for a systemic screening for metastatic bone disease.MRI with TIM techniques has higher spatial resolution for bone marrow than that in SPECT.
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