Study of haemoglobin saturation with Mössbauer spectroscopy

Red blood cells from normal subjects, Hodgkin's lymphoma and acute leukaemia have been investigated. Preliminary Mossbauer spectroscopy results in seven patients have shown a high haedmoglobin saturation. Independent measurements of pH, pCO2, pO2, DPG and P50, are in agreement with the Mossbauer data. These results give indication that the evaluation of haemoglobin saturation could be an information to be used in the clinical follow up of these hematological malignancies.