Sarcomatoid Carcinoma of Colon: Report of a Case of Long-Term Survival with Disease

Sarcomatoid carcinoma of colon is an extremely rare biphasic tumor characterized by a combina- tion of malignant epithelial and sarcomatoid cells. The known characteristics are rapid growth, high rate of recurrence and metastasis, drugs resistance and poor prognosis with median survival less than 6 months. Precise diagnosis warranted histological examination, immunohistochemistry study and exclusion of other diseases, such as carcinosarcoma, sarcomatous mesothelioma and stromal tumor. Herein we report a case of patient who had a sarcomatoid carcinoma of ascending colon and still been alive for 44 months with liver and peritoneal metastasis after two subsequent operations and multiple cycles of chemotherapy. By far, only two patients with colon sarcomatoid carcinoma were reported to survive longer than this case, which deserved to be researched in de- tails on diagnosis, clinical characteristics, therapy and outcome.