Ineffective Motility Disorder

Ineffective esophageal motility (IEM) describes esophageal body hypomotility detected during manometry. The concept of IEM was first established in 1997 using standard manometry, and the definition has changed over time due to the advent of high-resolution manometry (HRM). The latest Chicago Classification (version 3.0) defines IEM during HRM as frequent (≥50%) weak distal esophageal contractions (distal contractile integral (DCI) < 450 mmHg·cm·s).