DNA repair processes involved with the hypoxia-activated prodrug evofosfamide (TH-302): comparison to cisplatin and temozolomide

Vasquez et al. Targeting and processing of site-specific DNA interstrand crosslinks. Env and Mol Mut 51: 527-339, 2010 Wang et al. Differential contributory roles of nucleotide excision and homologous recombination repair for enhancing cisplatin sensitivity in human ovarian cancer cells Mol Cancer 10: 24-30, 2011 Hermisson et al. O-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells. J Neurochem 96: 766-776, 2006 Kat et al. An alkylation-tolerant, mutator human cell line is deficient instrand-specific mismatch repair. PNAS. 90: 6424-6428, 1993 Meng et al., Molecular and cellular pharmacology of the hypoxia-activated prodrug TH302. Mol Cancer Ther 11 74