[Using peripheral perfusion index and venous-to-arterial CO(2) difference/arterial-central venous O(2) difference ratio to assess lactate clearance in septic patients after resuscitation].

Objective The relationship of venous-to-arterial CO2 difference(Pv-aCO2)/arterial-central venous O2 difference (Ca-vO2) ratio, peripheral perfusion index(PI) and lactate clearance(LC) were investigated during resuscitation in septic patients. And, the meaning of the combination PI and Pv-aCO2/Ca-vO2 ratio to interpret incoherence of lactate clear was explored. Methods The patients with sepsis were prospectively observed, who admitted to critically care medicine department of Peking Union Medical College Hospital. The hemodynamic parameters, simultaneous arterial and central venous blood gas analysis and PI were obtained at the enrollment (T0) and 8 hours (T8) during resuscitation. The lactate clearance was defined as 8h-LC≥10% and non-lactate clearance was defined as 8h-LC ≤ 10%. Additionally, the patients were divided as three sub-groups according to the PI value at T8: the normalized PI group with PI≥1.4,the mild impaired PI with 1.4

Keywords:

• Resuscitation
• Cardiology
• Peripheral perfusion
• Internal medicine
• Medicine
• Hemodynamics
• Venous blood
• Risk factor
• Sepsis
• lactate clearance
• significant difference

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