Orodental abnormalities in limb malformation syndromes: A review article

The regular synchronization during development of an embryo results in the normal formation of his/her structures. The deviation from this harmony produces malformations. The pleiotropic effects of similar genes that contribute in the growth of limb and oral structures produce concurrent abnormalities indeed. The present review gives a brief hint at the shared causative genes of both limb and orodental structures. The nosology either of skeletal and limb malformations or of orodental findings and the types of orodental anomalies were reported in these syndromes. Pathognomonic orodental features and Egyptian experiences are emphasized.