Eosinophilic Cholecystitis Associated with Papillary Hyperplasia of Gall Bladder

Eosinophilic cholecystitis (EC) is a rare entity that presents in a manner comparable to acute cholecystitis. The diagnosis is based on classical symptoms of cholecystitis with the presence of eosinophils (>90%) within the gallbladder. EC has been reported alone (idiopathic EC) or in combination with manifestations such as eosinophilic cholangitis, hypereosinophilic syndromes, and parasitic infestations. Papillary hyperplasia of gallbladder occurs in the setting of cholelithiasis, inflammatory lesion of gallbladder, primary sclerosing cholangitis or ulcerative colitis. To the best of our knowledge of the literature reviewed, papillary hyperplasia has never been reported in a setting of eosinophilic cholecystitis. We report a case of 30 years old female presenting with idiopathic eosinophilic cholecystitis associated with papillary hyperplasia of gallbladder in the year 2011 at PGIMS Rohtak (India). Hereby we report coexistence of these two entities never described together.