Immobilized Hepatic Enzymes as a Tool in Extracorporeal Detoxification

Of the proteins, enzymes are one of the most important and specialized classes. They act as the essential catalyst of a wide number of chemical reactions linked to the intermediate metabolism of cells. In the last 10 years, the knowledge and technology of enzyme isolation have progressed significantly and a better understanding of the working mechanisms of enzymes has been achieved (Luisi 1979). Many kinds of enzymes have been widely used in the medical (Wolf and Rosenberger 1977), food (Reed 1975) and synthetic chemical industries (Jones et al. 1974).