Renal Angiomyolipoma With Cardiac Extension in Patient With Tuberous Sclerosis Complex

A 26-year-old woman with a clinical diagnosis of tuberous sclerosis complex, presenting the classical triad of seizures, mental retardation, and facial angiofibromas and reporting tachycardia, dyspnea during moderate physical activity, and 3 episodes of syncope in the past 30 days, was admitted to our hospital. Echocardiography revealed right cardiac chambers with increased dimensions related to a large echogenic tumor with an inferior component within the inferior vena cava (Figure 1). Computed tomography of the chest and abdomen without iodinated venous contrast media depicted a large tumor arising from the right kidney with adipose tissue, extending superiorly via inferior vena cava with right cardiac chambers involvement (Figure 2). MRI of the abdomen and heart showed the same large right kidney tumor with high signal intensity in T1- and T2-weighted images, signal intensity loss in T2-weighted images with fat saturation, and enhancement after the use …