Synthesis and evaluation of azaindole-α-alkyloxyphenylpropionic acid analogues as PPARα/γ agonists
2006
Abstract A series of azaindole-α-alkyloxyphenylpropionic acid analogues was synthesized and evaluated for PPAR agonist activities. Structure–activity relationship was developed for PPARα/γ dual agonism. One of the synthesized compound 7a was identified as a potent, selective PPARα/γ dual agonist.
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