Features and outcome of AIH patients without elevation of IgG

ABSTRACT Background Ap=0.0012). Patients of the control group had not only higher IgG-levels (29.5±5.8 vs 12.5±3.2 g/L;p Autoantibody titres were higher in the typical AIH group, but not when controlled for IgG-levels. Conclusions Compared to AIH with typical biochemical features, patients with normal IgG-levels at diagnosis (i) show similar biochemical, serological and histological features and comparable treatment response, (ii) appear to lack the selective elevation of serum IgG-levels observed in typical active AIH disease, (iii) may present a subgroup with a higher chance of successful drug withdrawal.