Impairments of Endocrine Functions: Case Studies

Tributyltin (TBT), an organometallic molecule, is one of the most potent pesticides ever introduced into the environment. Its introduction into marine ecosystems is primarily attributable to its use as the active compound in antifouling paints. Fouling is causedCONTENTS9.1 Imposex 219 9.1.1 Inputs of Tributyltin into Marine Waters 219 9.1.2 Imposex: A Bioindicator Specic for TBT Contamination 2209.1.2.1 TBT Is Responsible for Masculinization of Female Gastropods ...... 220 9.1.2.2 Relation between Imposex Development and TBTContamination Levels 220 9.1.2.3 Do Any Other Factors Inuence Imposex Development? 2219.1.3 Biological Mechanisms for Imposex Development 222 9.1.4 Temporal Evolution of TBT Contamination 223