Способ объективной оценки тяжести микроциркуляторных нарушений у больных системной склеродермией

The based on examination of 78 patients with systemic scleroderma and secondary Raynaud's phenomenon using the method of laser Doppler flowmetry (LDF) («ЛАЗМА» Russia) was offer the method for objective estimation of microcirculatory abnormalities. It was concluded that the more informative indexes of LDF are vasomotion activity, relation between high and low frequency oscillation, the reaction of capillars in occlusal test, endothelial dependence component and reduction of blood flow after nitroglycerin. The authors proposed the predictable criteria for the efficiency of vasodilatation therapy. Proposed method may used for measuring of heaviness Raynaud's phenomenon in patients with systemic sclerosis and for diagnose adecquate of vasodilatations treatment.