CYP2C19 and CYP3A4 Activity and ADP-induced Platelet Reactivity in Prasugrel- or Ticagrelor-treated STEMI Patients: Monocentric Study in PRAGUE-18 Trial Participants

Abstract We assessed the contribution of CYP2C19 and CYP3A4 metabolic activity to the ADP-induced platelet aggregation 1h and 24h after a loading dose of 60 mg prasugrel or 180 mg ticagrelor in pat...