Pain and Physical/Psychological Symptoms in Ambulatory Patients with HIV (317-B)

reported no or mild pain, 43% were not frail, 35.2% were pre-frail, and 21.8% were frail. Of participants who reported moderate or greater pain, 16.2% were not frail, 34.1% were pre-frail, and 49.8% were frail. Overall, frailty status was significantly associated with pain self-report, p < 0.01. The odds of being pre-frail was higher by a factor of 2.52 (2.13, 2.19), p < 0.05 for persons with moderate or greater pain compared to those who were not frail. The odds of being frail was higher by a factor of 5.52 (4.49, 6.64), p < 0.05 for persons with moderate or greater pain compared to those who were not frail. Conclusion. The concept of ‘‘pain homeostenosis’’ is supported by our findings. Implications for research, policy, or practice. Research is needed to evaluate pain management in mitigating the relationship between pain and frailty.