A kind of purification process of Imatinib
2017
The present invention relates to a kind of purification process of Imatinib.The characteristics of methods described has simple technique, safety and environmental protection, low cost, favorable reproducibility, can industrialize large-scale production.The content of (3 pyridine radicals) 2 aminopyrimidines of genotoxicity impurity N (aminomethyl phenyl of 5 amino 2) 4 in Imatinib can be down to below the 2ppm of pharmacopoeial requirements by methods described, and product purity is up to more than 99.8%.
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