Derivatives of L-adenosine and L-guanosine as substrates for human deoxycytidine kinase.

Abstract A series of analogues of L-adenosine and of L-guanosine, including s-L-dA, s-L-Ado, s-L-araA, and s-L-dG, have been shown to be substrates of human deoxycytidine kinase thus demonstrating the complete lack of enantioselectivity of this enzyme.