MicroRNA-21 inhibits Serpini1, a gene with novel tumour suppressive effects in gastric cancer ☆

Sumitaka Yamanaka,Alexandru Olaru,Fangmei An,Delgermaa Luvsanjav,Zhe Jin,Rachana Agarwal,Ciprian Tomuleasa,Irinel Popescu,Sorin Alexandrescu,Simona Dima,Mihaela Chivu-Economescu,Elizabeth A. Montgomery,Michael Torbenson,Stephen J. Meltzer,Florin M. Selaru

MicroRNA-21 inhibits Serpini1, a gene with novel tumour suppressive effects in gastric cancer ☆

2012

Sumitaka Yamanaka
Alexandru Olaru
Fangmei An
Delgermaa Luvsanjav
Zhe Jin
Rachana Agarwal
Ciprian Tomuleasa
Irinel Popescu
Sorin Alexandrescu
Simona Dima
Mihaela Chivu-Economescu
Elizabeth A. Montgomery
Michael Torbenson
Stephen J. Meltzer
Florin M. Selaru

Background A thorough understanding of gastric cancer at the molecular level is urgently needed. One prominent oncogenic microRNA, miR-21, was previously reported to be upregulated in gastric cancer.

Keywords:

Cancer
Three prime untranslated region
Diabetes mellitus
microRNA
Transfection
SERPINI1 gene
Gene
Downregulation and upregulation
Biology
Bioinformatics
General surgery
Cancer research
molecular level
Medicine

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