Efficacy and Safety of Linagliptin Co-Administered with Low-Dose Metformin Once Daily Versus High-Dose Metformin Twice Daily in Treatment-Naïve Patients with Type 2 Diabetes: a Double-Blind Randomized Trial

Linong Ji,Bernard Zinman,Sanjay Patel,Jinfeng Ji,Zelie Bailes,Sandra Thiemann,Thomas Seck

Efficacy and Safety of Linagliptin Co-Administered with Low-Dose Metformin Once Daily Versus High-Dose Metformin Twice Daily in Treatment-Naïve Patients with Type 2 Diabetes: a Double-Blind Randomized Trial

2015

Linong Ji
Bernard Zinman
Sanjay Patel
Jinfeng Ji
Zelie Bailes
Sandra Thiemann
Thomas Seck

Introduction The aim of this study was to investigate the efficacy and safety of linagliptin + low-dose (LD) metformin once daily versus high-dose (HD) metformin twice daily in treatment-naive patients with type 2 diabetes.

Keywords:

Metformin
Linagliptin
Randomized controlled trial
Diabetes mellitus
Anesthesia
Type 2 diabetes
Pharmacology
Type 2 Diabetes Mellitus
Medicine
Tolerability
Internal medicine
Urology
once daily

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