Mural thickening of the gallbladder? Look to the heart of the problem

Abstract The differential diagnosis for mural thickening of the gallbladder is broad and includes many extra-cholecystic conditions, especially in pediatrics. Primary cholecystitis is a rare cause of right upper quadrant pain in children Learning Objective Mural thickening of the gallbladder in the pediatric patient should prompt clinicians to think broadly about its etiology spanning several organ systems, including cardiac disease.