The role of micronutrients in thyroid dysfunction

Thyroid hormones are essential for normal growth and development in children. Nutritional factors are closely related to thyroid dysfunction due to deviation from normal physiology of the gland. Iodine, a main constituent of thyroid hormones (T3 and T4), deficiency is one of the commonest causes of hypothyroidism in children and adults, worldwide. Other micronutrients, such as Cruciferous vegetables, Pearl Millet, Soy products and Cassava, were also attributed to cause thyroid dysfunction. Environmental factors, namely, contamination of water with goitrogens could also contribute to the aetiology of goitre in some endemic areas. Dietary advice and avoidance of excessive use of goitrogens in diet are part of guidance on nutritional safety that needs to be established, especially in the areas of endemicity.