Steroid hormone receptors in struma

Oestradiol and progesterone receptors occur in different hormonally dependent tissues. The presence and number of steroid receptors in malignant breast tumours is well known. Endocrine treatment is effective. An attempt was made to quantify the oestradiol and progesterone receptors in human goitre. The behaviour of steroid receptors was studied in the cytosol of tissue samples from 33 surgically-treated patients. Neither oestradiol nor progesterone receptors were found in human goitre tissue.