Pathophysiology of unilateral ischemia-reperfusion injury: importance of renal counterbalance and implications for the AKI-CKD transition.

Aaron J. Polichnowski,Karen A. Griffin,Hector Licea-Vargas,Rongpei Lan,Maria M. Picken,Jainrui Long,Geoffrey A. Williamson,Christian Rosenberger,Susanne Mathia,Manjeri A. Venkatachalam,Anil K. Bidani

Pathophysiology of unilateral ischemia-reperfusion injury: importance of renal counterbalance and implications for the AKI-CKD transition.

2020

Aaron J. Polichnowski
Karen A. Griffin
Hector Licea-Vargas
Rongpei Lan
Maria M. Picken
Jainrui Long
Geoffrey A. Williamson
Christian Rosenberger
Susanne Mathia
Manjeri A. Venkatachalam
Anil K. Bidani

Unilateral ischemia-reperfusion (UIR) injury leads to progressive renal atrophy and tubulointerstitial fibrosis (TIF) and is commonly used to investigate the pathogenesis of AKI- CKD transition. Wh...

Keywords:

Diabetes mellitus
Acute kidney injury
Fibrosis
Hypoxia (medical)
Biology
Ischemia
Pathogenesis
Pathophysiology
Cardiology
Reperfusion injury
Biochemistry
Internal medicine
tubulointerstitial fibrosis
Renal blood flow
Renal function

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