FGFR4 Promotes Stroma-Induced Epithelial-to-Mesenchymal Transition in Colorectal Cancer

Rui Liu,Jingyi Li,Ke Xie,Tao Zhang,Yunlong Lei,Yi Chen,Lu Zhang,Kai Huang,Kui Wang,Hong Wu,Min Wu,Edouard C. Nice,Canhua Huang,Yuquan Wei

FGFR4 Promotes Stroma-Induced Epithelial-to-Mesenchymal Transition in Colorectal Cancer

2013

Rui Liu
Jingyi Li
Ke Xie
Tao Zhang
Yunlong Lei
Yi Chen
Lu Zhang
Kai Huang
Kui Wang
Hong Wu
Min Wu
Edouard C. Nice
Canhua Huang
Yuquan Wei

An FGF receptor is found to be pivotal for the process by which the tumor stromal microenvironment triggers conversion of epithelial cancer cells to mesenchymal phenotypes that are more invasive and metastatic.

Keywords:

Stroma
Stromal cell
Cancer cell
Epithelial–mesenchymal transition
Colorectal cancer
Mesenchymal stem cell
Immunology
Fibroblast growth factor receptor 4
Phenotype
Medicine
Pathology
epithelial cancer

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