Coexistence of gain-of-function JAK2 germ line mutations with JAK2V617F in polycythemia vera.
2016
To the editor:
Philadelphia chromosome–negative myeloproliferative neoplasms (MPNs) can be viewed as clonal premalignant disorders that precede development of acute leukemia wherein the order of mutation acquisition, together with environmental insults such as inflammation, matters. MPN disease-
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