Analysis of antifungal resistance genes in Candida albicans and Candida glabrata using next generation sequencing

Introduction/Objectives An increase in antifungal resistant Candida strains has been reported in recent years. The aim of this study was to detect mutations in resistance genes of azole-resistant, echinocandin-resistant or multi-resistant strains using next generation sequencing technology, which allows the analysis of multiple resistance mechanisms in a high throughput setting.