Interaction Networks of Proteins

Proteins are often the ultimate expression of information encoded in the DNA (deoxyribonucleic acid). Proteins interact with other proteins, nucleic acids, and a variety of small molecules to affect cellular function. Such interactions assume the form of a vast network, portions of which are activated in a spatial and temporal manner. Understanding the makeup, properties and behaviour of this network promises to reveal many important details of the biology of organisms, ultimately helping better our knowledge of molecular and biochemical events that take place at the cellular level. Keywords: protein-protein interactions; functional interactions; protein interaction networks; protein-DNA regulation networks; transcriptional regulatory networks; COGRIM