Значение провоспалительных цитокинов в секрете ротовой полости у больных целиакией

There has been studied the activity of anti-inflammatory cytokines (IL-1, TNF-a) in the secretion of mouth cavity of children with celiacia. The high levels of these magnitudes were marked of 100% and 80% of patients respectively. There has been stated the correlation of the activity TNF-a with the magnitude of the deficiency of body mass, level of endogenic intoxication, the evidence of atrophic changes of mucous membrane of small intestine. The degree of the increase of the activity IL-1 was defined by the extent of lymphoplasmocytic infiltration of the own lamella of mucous membrane of small intestine. The received data allowed to work out the additional criteria of diagnostics and assessment of inflammatory process in the intestinal mucous membrane.