Development of pH/Glutathione Responsive Theranostic Agents Activated by Glutathione S-transferase π for Human Colon Cancer

Ji Liu,Xin Liu,Jianqiang Qian,Chi Meng,Peng Zhu,Jiaying Hang,Yaling Wang,Biao Xiong,Xiaodong Qiu,Weizhong Zhu,Yumin Yang,Yanan Zhang,Yong Ling

Development of pH/Glutathione Responsive Theranostic Agents Activated by Glutathione S-transferase π for Human Colon Cancer

2020

Ji Liu
Xin Liu
Jianqiang Qian
Chi Meng
Peng Zhu
Jiaying Hang
Yaling Wang
Biao Xiong
Xiaodong Qiu
Weizhong Zhu
Yumin Yang
Yanan Zhang
Yong Ling

Two novel theranostic agents HJTA and HJTB have been designed and synthesized by covalently linking a β-carboline derivative, with antitumor activities and pH-responsive fluorescence, with a 2-exom...

Keywords:

Chemistry
Glutathione
glutathione s transferase π
Biochemistry
human colon cancer

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