pAra cCticaol snynvtheetnic iperoncetd uPresractical Synthesis of Alkyl and Aryl Oxime Esters
2014
A facile access to the synthesis of alkyl and aryl oxime esters of ketoximes and aldoximes in high yields (90–97%) is reported.
The reactions were performed using N-[3-(methylamino)propyl]-N′-ethylcarbodiimide hydrochloride (EDCI) reagent in the presence of 4-
(dimethylamino)pyridine (DMAP) as a catalyst at room temperature. The isolation and purification of products is very simple and in cases
where product is solid, column chromatography is avoided.
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