Spontaneous regression of two giant basal cell carcinomas in a single patient after incomplete excision

Background. Spontaneous regression of small basal cell carcinoma has been report ed. For giant basal cell carcinoma, however, no spontaneous regression has been de scribed to date. Case report. We present a patient with two independent giant basal cell carcinomas over the left clavicle and the lower back, measuring 7 x 12 cm and 18 x 20 cm, respec tively. Both tumors were excised incompletely (R2) and the patient refused followup resections. After 52 and 16 months, respectively, no signs of recurrence were ob served. Conclusion. Incompletely excised giant basal cell carcinomas can regress sponta neously. A watch-and-wait approach after incomplete resection may be pragmatic to avoid mutilating follow-up resections in patients refusing further surgery.