195-LB: How Does a Prepregnancy Weight Loss Program Affect Gestational Diabetes Risk?

Although numerous organizations recommend that women with obesity or overweight lose weight prior to pregnancy, to our knowledge no data have addressed whether interventions that help women lose weight before pregnancy affect gestational diabetes risk in mothers. We successfully randomized 164 pregnant women to receive either a behavioral weight-loss intervention (n = 87) or usual care (n = 77) from prepregnancy through delivery. Intervention participants achieved significantly more weight loss before pregnancy than the usual care group (3.7 kg vs. 0.5 kg; p= Disclosure E.S. LeBlanc: None. N. Smith: None. K. Vesco: None. A.G. Rosales: None. V.J. Stevens: None. Funding National Institute of Diabetes and Digestive and Kidney Diseases (R01DK0099882)