Palladium-catalyzed oxidative homocoupling of 2-arylquinazolinones

Abstract Pd-catalyzed oxidative homocoupling of 2-arylquinazolinones was successfully developed for the direct construction of biaryls via C-H bond activation. New well-defined structure that possessed two quinazolinone units was obtained with high efficiency and atomic economy. The protocols offer an efficient approach to the synthetically useful and functionalized biaryls in good yields using quinazolinone as a directing group.