PD22-04 AUGMENTATION URETHRAL RECONSTUCTION USING TISSUE-ENGINEERED ORAL MUCOSA GRAFT MUKOCELL®

INTRODUCTION AND OBJECTIVES:One-stage augmentation urethral reconstruction with buccal mucosa is the method of choice in recurrent urethral strictures and achieves good results up to 75-85% with long-term follow up. Complications of harvesting buccal mucosa are swelling and scarring, injuries to the salivary gland orifices, and problems with the intake of food and restriction of the opening of the mouth. We examined the feasibility of tissue-engineered oral mucosa grafting in urethral reconstruction.METHODS:Between 05/2016 and 10/2018, a total of 65 patients with strictures of the anterior urethra underwent an augmentation urethroplasty with MukoCell® (by UroTiss Europe GmbH). Mean patient age was 59 years (range 20 to 87) with mean 2,6 previous endoscopic or anastomotic procedures (range 0 to 8). There were 35 patients with bulbar strictures (53.8%), 15 with penobulbar (23.1%), 10 with penile (15.4%), 4 with membranous (6,2%) and 1 had simultaneously a bulbar and a penile stricture (1.5%) respectively. P...