How Representative is the GMALL of the German Population

It is usually not possible to generalise conclusions from a therapeutic study to the whole population because of the select nature of the study population. The situation seems to be, however, different in the German Multicentre Study Group For Adult ALL on acute lymphoblastic leukaemia GMALL (Gokbuget et al. 2000), age 15-64, because more than a hundred centres are recruiting in Germany.