Three cases of pityriasis rubra pilaris successfully treated with cyclosporin A.

Background: Pityriasis rubra pilaris (PRP) is reported to respond poorly to cyclosporin A (CsA). Objective: We attempted to determine the efficacy of CsA in the treatment of classic adult-type PRP. Methods: Three patients with classic adult-type PRP were treated with 5 mg/kg/day CsA. Results: A sustained clinical response was achieved within 2–4 weeks of therapy. Relapses were noted when the CsA dose was decreased to 1.2 mg/kg/day. Conclusion: CsA should be considered in the treatment of classical adult-type PRP.