Sarcoma botryoides a management dilemma: A review of two cases

2014 
Introduction: sarcoma botryoides is a rare and rapidly growing tumor affecting primarily the female genital tract of children. It presents as bleeding per vaginum or as a polypoid fleshy mass protruding through the vagina. treatment is surgery combined with multidrug chemotherapy. In developing environment, one has to contend with late presentation, availability and affordability of cytotoxics and the surgical options available at advanced stage, their acceptability, their management postoperative and their impact on quality of life. case series: the first case was a four-yearold child who presented with a rapidly growing mass protruding per vaginum, intermittent vaginal bleeding and difficulty in passing stool and urine. she had examination under anesthesia and biopsy. Histology confirmed sarcoma botryoides. Her parents opted for multidrug chemotherapy and was treated with a combination of cylophosphamide, vincritine and doxorubicin. she had six courses of the drugs with remarkable improvement in symptoms and the tumor regressed almost completely. Patient was subsequently lost to follow-up. the second case was a six-month-old child who presented with vaginal bleeding, vaginal growth and abdominal swelling. Histology confirmed
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