Basic research conducted on alloplant biomaterials

Purpose. To reduce antigenicity of allografts and stimulate their replace- ment by natural recipient tissues. Methods. Experimental allotransplantation of different tissues (fascias, tendons, derma, fat, etc.) with histological, histochemical, electron microscopical, electron histochemical examination 3, 5, 7, 14, 21, 30, 60, 120, 180 and 360 days postoperatively. Results. Allografts of different tissues with glucosaminoglycans extracted from collagen fibers have low antigenicity and can be replaced by natural tissues. Allografts with these properties were named 'Alloplant'. Conclusions. Alloplant biomaterials can selectively stimulate natural tissue regenera- tion. Hence, Alloplant biomaterials can be utilized in surgery for the restoration of differ- ent tissues. (Eur J Ophthalmol 1999; 9: 8-13)