An Evaluation of Catheter-Related Bloodstream Infections in Intensive Care Units

Aim: This study aims to study the risk factors that are related with the development of bloodstream infections in the patients hospitalized in intensive care units (ICUs). Materials and Methods: We have prospectively examined the risk factors and microbiologic analyses of 18 patients with catheter-related blood stream infections (CR-BSI) who were selected from among 300 patients at ICU with central venous catheters (CVC) for 12 months (between August 2011 and August 2012). Results: The mean duration of the catheterization was 15,19±5,977 days. The sensitivity and specificity of the time factor for receiving positive signal from cultures of CVC and blood samples were 88.8% and 93%, respectively. The CR-BSI attack rate was 20.9%. Metabolic disorders, duration of hospitalization in ICU, urinary catheterization, longer length of CVC duration, and whether CVC was used for other tests were found to be significant risk factors for the development of CR-BSI (p<0,001). Methicilin-resistant coagulase-negative staphylococcus (MRCNS) was detected in 6 (33.3%) cases while Acinetobacter baumanii was detected in 2 (11.1%) cases and polymicrobial agents were detected in 5 cases (27.7%). We also detected the following bacteria in 1 (5,6%) patient (for each) Pseudomonas aeruginosa, diphteroid bacilli, Aeromonas veronii, methicillin-susceptible Staphylococcus aureus, and Klebsiella pneumoniae. Conclusion: In this study, metabolic disorders and CVC related factors were determined as risk factors for CR-BSI development. Taking these preventable factors into consideration and proper use of infection control measurements will provide significant decrease in CR-BSI rates. However, there is need for new scientific approaches on the diagnosis, treatment, and prevention for CR-BSI. Anahtar Kelimeler: Central Venous Catheter; Catheter-Related Bloodstream Infection; Intensive Care Unit, Bacteremia. Yogun Bakim Unitelerinde Gelisen Kateter Iliskili Kan Dolasim Enfeksiyonlarinin Irdelenmesi